This article offers an in-depth analysis of the bullish signals released during the U.S. SEC Roundtable in June 2025, examining their far-reaching implications for DeFi compliance, institutional capital inflows, the legal recognition of self-custody, and the emergence of innovative exemption mechanisms. It also proposes a strategic positioning framework—from retail to institutional investors—aimed at capturing the structural opportunities brought about by increased regulatory clarity in the next crypto bull market. A must-read for those focused on DeFi, compliance, RWAs, and crypto policy developments.